Effects of Dietary Protein and Fat Contents on Renal Function and Inflammatory Cytokines in Rats with Adriamycin-Induced Nephrotic Syndrome

Table 1

Body weights, food intakes, FER, and organ weights.

	LPHF^(1)	HPLF^(2)
Initial body weight (g)	374.3 ± 11.4	366.4 ± 16.4
Final body weight (g)	415.5 ± 13.0	411.5 ± 12.1
Weight gain (g)	41.2 ± 10.3	40.0 ± 8.5
Calories intake (kcal/day)	58.4 ± 0.5	58.0 ± 0.3
FER^(3)	0.4 ± 0.1	0.5 ± 0.1
Liver (g)	12.2 ± 0.6	11.9 ± 1.0
Spleen (g)	0.7 ± 0.1	0.8 ± 0.2
Kidney (g)	2.6 ± 0.1	3.4 ± 0.6*
Heart (g)	1.2 ± 0.1	1.2 ± 0.1

⁽¹⁾ LPHF: weekly intraperitoneal injection of adriamycin (2 mg/kg BW) for 6 weeks thereafter a 7% protein and 40% fat diet for 5 weeks.
⁽²⁾HPLF: weekly intraperitoneal injection of adriamycin (2 mg/kg BW) for 6 weeks thereafter a 30% protein and 7% fat diet for 5 weeks.
⁽³⁾FER: food efficiency ratio: (weight gain (g))/(food consumed (kcal)/day).
*Statistical difference between the HPLF and LPHF groups by Student’s 𝑡-test at 𝑃<.05.