Effects of Dietary Protein and Fat Contents on Renal Function and Inflammatory Cytokines in Rats with Adriamycin-Induced Nephrotic Syndrome

Table 2

Serum levels of inflammatory cytokines.

	LPHF^(1)	HPLF^(2)
Proinflammatory cytokines (pg/mL)
IL-1𝛽	23.5 ± 1.1	29.3 ± 9.0
IL-6	113.4 ± 84.2	95.8 ± 23.5
TNF-𝛼	3.0 ± 0.3	2.8 ± 0.2
Anti-inflammatory cytokines (pg/mL)
IL-4	23.8 ± 2.4	25.8 ± 3.6
IL-10	3.1 ± 0.4	3.7 ± 0.9
IL-13	44.7 ± 4.4	52.4 ± 19.6

⁽¹⁾LPHF: weekly intraperitoneal injection of adriamycin (2 mg/kg BW) for 6 weeks thereafter a 7% protein and 40% fat diet for five weeks.
⁽²⁾HPLF: weekly intraperitoneal injection of adriamycin (2 mg/kg BW) for 6 weeks thereafter a 30% protein and 7% fat diet for five weeks.
No statistical difference between the LPHF and HPLF groups by Student’s 𝑡-test at 𝑃<.05.