Mediators of Inflammation / 2012 / Article / Tab 2

Research Article

A Comparative In Vitro Study of the Effects of Separate and Combined Products of Citrus e fructibus and Cydonia e fructibus on Immunological Parameters of Seasonal Allergic Rhinitis

Table 2

Differences in mean cytokine scores after one-day PBMC cultures in the SAR group, healthy group, and total group (grass pollen stimulation minus medium stimulation).

CitrusCydoniaCitrus/CydoniaCitrus versus Cydonia Citrus versus Citrus/Cydonia valueCydonia versus Citrus/Cydonia value

IL-1β*SAR8.2 (7.0)20.6 (5.0)14.6 (8.9) n.s.n.s.
Healthy2.4 (2.3)17.6 (6.7)18.8 (8.0) n.s.
Total group5.3 (5.8)19.1 (5.8)16.7 (8.3)
IL-10SAR64.0 (14.4)59.2 (10.1)54.0 (8.2)n.s.n.s.n.s.
Healthy53.0 (15.2)65.2 (14.4)69.6 (3.9)n.s.n.s.n.s.
Total group58.5 (15.1)62.2 (12.1)61.8 (10.2)n.s.n.s.n.s.
TNF-αSAR94.8 (9.0)182.2 (15.2)162.8 (37.4) n.s.
Healthy105.6 (25.2)160.2 (13.2)143.2 (23.9) n.s.
Total group100.2 (18.7)171.2 (17.7)153.0 (31.3)
IFN-γSAR3.0 (1.9)6.8 (1.1)6.0 (1.2) n.s.
Healthy3.0 (1.6)6.0 (1.4)5.4 (1.1) n.s.
Total group3.0 (1.6)6.4 (1.3)5.7 (1.2)
IL-10/
TNF-α
SAR0.7 (0.1)0.3 (0.1)0.4 (0.1) n.s.
Healthy0.5 (0.2)0.4 (0.1)0.5 (0.1)n.s.n.s.n.s.
Total group0.6 (0.2)0.4 (0.1)0.4 (0.1)

* The mean score (SD) in pg/mL is presented for all cytokine measurements; n.s., not significant.

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