Mediators of Inflammation / 2012 / Article / Tab 3

Research Article

A Comparative In Vitro Study of the Effects of Separate and Combined Products of Citrus e fructibus and Cydonia e fructibus on Immunological Parameters of Seasonal Allergic Rhinitis

Table 3

Differences in mean scores after seven-day PBMC cultures in the SAR group, healthy group, and total group (grass pollen stimulation minus medium stimulation).

CitrusCydoniaCitrus/Cydonia value Citrus versus Cydonia value Citrus versus Citrus/Cydonia value Cydonia versus Citrus/Cydonia

IL-10SAR88.4 (28.5)101.4 (19.5)115.2 (36.2)n.s.n.s.n.s.
Healthy76.4 (38.2)107.4 (16.5)102.4 (26.1)n.s.n.s.n.s.
Total group82.4 (32.4)104.4 (17.3)108.8 (30.5)n.s.n.s.
IL-5SAR509,8 (126.6)727.6 (95.5)619.0 (87.7) n.s.n.s.
Healthy358.0 (81.3)575.8 (98.6)711.4 (144.7) n.s.
Total group433.9 (128.3)651.7 (121.6)665.2 (122.9) n.s.
IL-13SAR1470 (390.3)1823.0 (185.7)1917.2 (277.7)n.s. n.s.
Healthy1589.2 (300.2)1864.2 (102.0)1765.4 (186.6)n.s.n.s.n.s.
Total group1529.6 (334.2)1843.6 (142.9)1841.3 (237.0)n.s.n.s.n.s.
IFN-γSAR666.8 (126.2)724.0 (105.2)621.4 (90.8)n.s.n.s.n.s.
Healthy558.0 (130.1)692.0 (58.4)571.4 (57.1)n.s.n.s.
Total group612.4 (133.7)708.0 (82.0)596.4 (76.2) n.s.
IFN-γ/
IL-5
SAR1.4 (0.5)1.0 (0.2)1.0 (0.2)n.s.n.s.n.s.
Healthy1.6 (0.4)1.2 (0.2)0.8 (0.2)n.s.
Total group1.5 (0.4)1.1 (0.2)0.9 (0.2) n.s.
IFN-γ/
IL-13
SAR0.5 (0.1)0.4 (0.1)0.3 (0.1)n.s.n.s.n.s.
Healthy0.4 (0.1)0.4 (0.1)0.3 (<0.1)n.s.n.s.n.s.
Total group0.4 (0.1)0.4 (0.1)0.3 (0.1)n.s.n.s.n.s.
IL-10/
IL-5
SAR0.2 (0.1)0.1 (<0.1)0.2 (0.1)n.s.n.s.n.s.
Healthy0.2 (0.1)0.2 (0.1)0.2 (0.1)n.s.n.s.n.s.
Total group0.2 (0.1)0.2 (<0.1)0.2 (0.1)n.s.n.s.n.s.
IL-10/
IL-13
SAR0.1 (<0.1)0.1 (<0.1)0.1 (<0.1)n.s.n.s.n.s.
Healthy<0.1 (<0.1)0.1 (<0.1)0.1 (<0.1)n.s.n.s.n.s.
Total group0.1 (<0.1)0.1 (<0.1)0.1 (<0.1)n.s.n.s.n.s.

* The mean score (SD) in pg/mL is presented for all cytokine measurements; n.s., not significant.

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