Circulating Cytokines and Growth Factors in Pediatric Pulmonary Hypertension
Added value of proteins toward outcome prediction. (a) Comparison of the ROC curves indicate an improvement in discriminative ability with the addition of the 4th PC calculated from the protein measurements. -indices for each model are also displayed. (b) The reclassification of estimated probabilities for the logistic regression model which included protein markers as a predictor versus the model based on PAP alone. The dots represent those observations associated with an event and the open circles with a nonevent. Higher percentages of events and nonevents are desired above and below the reference line, respectively. The corresponding reclassification index was significant () indicating a significant improvement in prediction with the addition of the proteins.