Deoxyribonuclease Is a Potential Counter Regulator of Aberrant Neutrophil Extracellular Traps Formation after Major Trauma
Figure 3
Values of cfDNA/NETs and DNase in the early septic phase. Highest values of cf-DNA/NETs and DNase in the range between the day before (−1), the day of (0), and the day after (+1) diagnosis of sepsis after major trauma. (a) cf-DNA/NETs values of patients with sepsis were significantly enhanced compared to patients with uneventful recovery () or healthy volunteers (). (b) Likewise values of DNase of patients who developed sepsis after major trauma were significantly enhanced compared to patients with uneventful recovery () or healthy volunteers (). The horizontal line across the boxplots represents the median, and the lower and upper ends of the boxplots are the 25th and 75th percentiles, respectively. Whiskers indicate the minimum and maximum values, respectively. * and ***.
