Symptoms, but Not a Biomarker Response to Inhaled Corticosteroids, Predict Asthma in Preschool Children with Recurrent Wheeze

Table 1

Characteristics at baseline for transient wheezers and true asthmatics.

	Transient wheeze; 𝑁=105	Asthma; 𝑁=65	Total; 𝑁=170
Mean age (SD)	3.3 (0.6)	3.3 (0.6)	3.3 (0.6)
Gender: male/female (𝑛)	55/50	37/28	92/78
Atopy^†, %*	20	35	26
Eczema, %	36	47	40
Use of ICS, %*	12	26	18
Use of short-acting 𝛽2-agonists, %*	31	54	40
Asthma first degree relatives, %	36	44	39
Smoking exposure, %	30	31	31

^∗𝑃<0.05 between transient wheezers and true asthmatics; ^†atopy is defined as a positive (≥0.35 kU/L); Phadiatop Infant test (Phadiatop Infant, Phadia, Uppsala, Sweden); SD: standard deviation.