Nuclear Localization of COX-2 in relation to the Expression of Stemness Markers in Urinary Bladder Cancer
Figure 1
Localization of COX-2 in urinary bladder cancer. COX-2 (red) was stained by an immunofluorescence method in urinary bladder tissues including normal (SH−) and cancer (SH+) tissues. (a) COX-2 was very weakly expressed in normal tissues. Scale bar is equal to 20 μm. (b) COX-2 staining was observed only in the cytoplasm of cancer cells. (c) COX-2 was strongly expressed in both the cytoplasm and nucleus of cancer cells. Arrows indicate nuclear positive staining. (d) COX-2 was strongly expressed in the nucleus of cancer cells. SH: S. haematobium infection.
