The EGF Receptor and HER2 Participate in TNF-α-Dependent MAPK Activation and IL-8 Secretion in Intestinal Epithelial Cells
Figure 7
Inhibition of HER2 tyrosine kinase activity (2.5 μM AG879) in addition to that of EGFR results in greater inhibition of ERK1/2 phosphorylation as compared to EGFR inhibition alone (10 μM) (a) in HT-29 cells. (b) is a loading control, 25 μM PD98058. Figure is representative of three separate experiments.
