The Absence of Nrf2 Enhances NF-𝜿B-Dependent Inflammation following Scratch Injury in Mouse Primary Cultured Astrocytes

Figure 4

ELISA analysis of protein level of proinflammatory cytokines. ELISA results revealed protein level of these cytokines were elevated in astrocytes after scratch as compared with sham control (𝑃<0.01). And they were much higher in Nrf2 KO astrocytes than in their WT counterparts (𝑃<0.01). (a) TNF-α. (b) IL-6. (c) IL-1β (*𝑃<0.01, compared with sham counterpart; ^#𝑃<0.01, compared with WT TBI).

(a)

(b)

(c)