Mediators of Inflammation

Clinical Study

Value of C-Reactive Protein in Predicting Left Ventricular Remodelling in Patients with a First ST-Segment Elevation Myocardial Infarction

Table 2

Angiographic and biochemical characteristics of the study population.
VariableOverall study population ( 𝑛 = 1 9 8 )Patients with LVR ( 𝑛 = 5 5 )Patients without LVR ( 𝑛 = 1 4 3 ) 𝑃 for comparison between groups with and without LVR
Angiographic indices
IRA: LAD/non-LAD 𝑛 (%)92 (46.5)/106 (53.5)32 (58.2)/23 (41.8)60 (42.0)/83 (58.0)NS
Multivessel coronary artery disease 𝑛 (%)119 (60.0%)38 (69.1%)81 (56.6%)NS
TIMI 3 flow in IRA 𝑛 (%)    
 Before pPCI55 (27.8)10 (18.2)45 (31.5)<0.05
 After pPCI185 (93.4)49 (89.1)136 (95.1)NS
TMPG 3 after pPCI 𝑛 (%)94 (46.1)30 (54.6)62 (43.4)NS
Patients with implanted stents 𝑛 (%)196 (99.0)54 (98.2)142 (99.3)NS
Abciximab use 𝑛 (%)49 (24.7)17 (30.9)32 (22.4)NS
Biochemical parameters
Creatinine ( πœ‡ mol/L)82.7 (72.0–95.9)82.7 (79.6–89.3)82.2 (70.7–97.2)NS
Admission glucose (mmol/L)7.6 (6.8–9.3)7.8 (6.8–9.6)7.4 (6.7–9.2)NS
TnImax (ng/mL) 46.3 (11.7–50.0)50.0 (15.3–50.0)36.7 (10.5–50.0)NS
CK-MBmax (U/L)102.5 (58.0–160.0)134.0 (87.0–206.0)95.0 (54.0–141.0)<0.01
LDL cholesterol (mmol/L)3.76 (3.23–4.45)3.75 (3.39–4.40)3.78 (3.21–4.45)NS
HDL cholesterol (mmol/L)1.32 (1.16–1.50)1.32 (1.19–1.50)1.34 (1.14–1.50)NS
Triglycerides (mmol/L)1.01 (0.67–1.59)0.98 (0.64–1.51)1.02 (0.69–1.59)NS
Leukocyte count on admission (103/ πœ‡ L)11.3 (9.1–13.3)12.0 (10.5–13.7)10.6 (8.7–12.8)<0.05
Leukocyte count 24 h after admission (103/ πœ‡ L)10.1 (8.6–11.7)10.3 (9.2–12.3)10.1 (8.2–11.3)<0.05
BNP on admission (pg/mL)51.9 (25.9–102.5)50.5 (25.3–121.0)52.8 (26.8–93.0)NS
BNP at discharge (pg/mL)124.8 (70.5–233.0)159.6 (74.6–358.2)114.0 (61.5–192.7)<0.05
BNP: B-type natriuretic peptide; CK-MBmax: maximal activity of izoenzyme MB of creatine kinase; HDL cholesterol: high-density-lipoprotein cholesterol; IRA: infarct-related artery; LAD: left anterior descending artery; LDL cholesterol: low-density-lipoprotein cholesterol; LVR: left ventricular remodelling; pPCI: primary percutaneous coronary intervention; TnImax: maximal concentration of troponin I; TIMI: Thrombolysis in Myocardial Infarction score; TMPG: TIMI myocardial perfusion grade.