IL-17 and IL-22 in Cerebrospinal Fluid and Plasma Are Elevated in Guillain-Barré Syndrome
Table 1
Demographic data and IL-17 and IL-22 levels in the cerebrospinal fluid (CSF) and plasma of Guillain-Barré syndrome (GBS) patients and healthy controls (HC).
GBS (n = 22)
HC (n = 18)
Female/male
8/14
7/11
Age
41.91 ± 13.16
39.11 ± 11.18
White blood cells in CSF (per μL)
1.32 ± 1.21
1.06 ± 0.94
Total protein level in CSF (mg/dL)
71.56 ± 30.79*
52.01 ± 12.81
Albumin level in CSF (mg/dL)
49.58 ± 25.33**
30.27 ± 11.71
Albumin level in plasma (g/L)
41.55 ± 12.56
43.67 ± 14.66
Qalb × 100
1.24 ± 0.60*
0.79 ± 0.45
IL-17 concentration in CSF (pg/mL)
24.77 ± 7.45*
18.70 ± 8.72
IL-17 level in plasma (pg/mL)
17.39 ± 4.87*
13.35 ± 4.54
IL-22 concentration in CSF (pg/mL)
25.38 ± 12.35***
8.19 ± 2.50
IL-22 level in plasma (pg/mL)
96.40 ± 52.28*
63.01 ± 27.22
Data are expressed as mean ± SD, student's t-test. *: Statistically significant in comparison with HC, *P < 0.05, **P < 0.01, ***P < 0.001. Qalb = CSF albumin/plasma albumin.
