Review Article

Possible Roles of Proinflammatory and Chemoattractive Cytokines Produced by Human Fetal Membrane Cells in the Pathology of Adverse Pregnancy Outcomes Associated with Influenza Virus Infection

Table 5

Physiological and pharmacological inhibitors for cytokine production in human fetal membranes.

PropertiesInhibitorsReferences

Antioxidant -Acetyl-L-cysteine[123]

Anti-inflammatory cytokinesIL-10[115118]
Activin A[119]

Anti-inflammatory compoundsSulfasalazine[122]

p38 MAK inhibitorsSKF86002[120]
SB203580 and SB202190[125]

NF-κB inhibitors
 Selective and competitive IKKβ inhibitorSC-514[126]
 Selective allosteric IKKβ inhibitorBMS 345541[126]
 IKK inhibitorEvodiamine[126]
 Nonselective IKK inhibitorWedelolactone[126]
 Partially selective IKKκ inhibitorButein[126]
 Inhibitor of NF-κB translocationCAPE[126]
 Inhibitor of the IKK complexParthenolide[126]
 Selective IKKβ inhibitorTPCA-1[126]

Phosphodiesterase 4 inhibitorRolipram[127]

PPAR-γ ligand15d-PGJ2[121]
Troglitazone[121]