Arginine-Based Inhibitors of Nitric Oxide Synthase: Therapeutic Potential and Challenges

Figure 2

Summary of the use of current methods of inhibitor design among arginine-based NOS inhibitors. For a description of individual approaches see the chapter “Current methods of inhibitor design among arginine-based NOS inhibitors”. The width of arrows indicates the proportion in total number of arginine-based inhibitors. Only compounds for which quantitative data on the inhibition of at least one NOS isoform have been published were considered for this summary.