Cytokines in Pericardial Effusion of Patients with Inflammatory Pericardial Disease

Table 1

Demographic characteristics of study patients.

Variable	All patients	aPE	vPE	CAD	P value*
	(𝑛=59)	(𝑛=22)	(𝑛=11)	(𝑛=26)
Men/women	39/20	10/12	8/3	21/5^#	<0.05
Age (years)	66.7±11.4	63.5±11.6	58.7±11.7	68.58±8.3^‡	<0.05
CAD	27 (46%)	1 (5%)	0	26 (100%)^#‡	<0.001
Hypertension	42 (71%)	11 (50%)	5 (45%)	26 (100%)^#‡	<0.001
Diabetes mellitus	12 (20%)	2 (4%)	0	10 (38%)^#‡	<0.05
Hypercholesterolemia	44 (75%)	14 (64%)	6 (55%)	24 (92%)^#‡	<0.05
Creatinine (mg/dL)	1.2±1.24	0.88±0.23	1.7±2.5	1.29±0.6^#	<0.05
Hemoglobin (g/L)	135 ± 18.77	138.86±15.6	124.36±22.72	137 ± 18.21	NS
Leukocytes (G/L)	8.53±2.81	8.62±3.11	9.78±2.99	7.61±1.98	NS
Protein (g/dL)	69.86±7.98	71.57±6.68^‡	63.18±9.11	72.06±6.63^‡	<0.05
C-reactive protein (mg/L)	21.88±46.61	24.76±48.66	43.46±66.13	3.25±4.47	NS

Values are mean ± SD or numbers of patients (percentage).
*Analysis of variance/chi-square or Fischer exact test.
^#𝑃<0.05 versus aPE; ^‡𝑃<0.05 versus vPE.
In 9 patients with CAD and 1 patient with aPE no biochemical data were available.
aPE: autoreactive pericardial effusion; vPE: viral pericardial effusion; CAD: coronary artery disease; NS: not significant.