Erythromycin Enhances Regulatory T-Cell Responses in a Rat Model of Smoke-Induced Lung Inflammation
Figure 1
Treatment with erythromycin protects against the smoking-induced emphysema in rats. The lung tissue sections from different groups of rats were subjected to H&E staining, and the alveolar airspace enlargement was assessed using MLI by two independent individuals in a blinded manner. Data are representative images or expressed as mean value ± SD of each group of rats () from five separate experiments. (a) Morphological changes in the lungs of rats (magnification × 100). (b) Quantitative analysis of alveolar airspace. Group N: rats exposed to regular air without any special treatment; Group C: rats exposed to regular air and were treated with erythromycin; Group S: rats exposed to smoking air and were treated with saline; Group E: rats exposed to smoking air and were treated with erythromycin daily for nine weeks beginning at the forth weeks smoking. *.
