Chemokine and Free Fatty Acid Levels in Insulin-Resistant State of Successful Pregnancy: A Preliminary Observation

Table 1

Characteristic of the subjects and serum concentrations of the molecules.

	Nonpregnant control	Normal pregnancy later than 28 weeks	Pregnancy-induced hypertension
𝑛	17	25	7
Gestational age at sampling (weeks)		33.2±0.7	32.3±0.8
BMI at sampling (kg/m^2)	20.3±0.4	23.9±0.5 *	24.5±0.6
BMI before pregnancy (kg/m^2)	20.3±0.4	20.5±0.4	20.9±0.9
Blood pressure
Systolic	106.3±1.8	107.3±1.8	174.8±2.0
Diastolic	73.1±1.2	58.8±1.6 *	100.3±2.6 **
MAP	84.1±1.1	74.9±1.5 *	107.3±17.9 **
FFA (μM)	155.62±29.17	153.68±16.23	236.54±31.89 **
Albumin (g/dL)	3.48±0.07	2.62±0.05 *	1.92±0.12 **
FFA/Alb	41.62±8.50	58.82±5.94 *	124.94±15.96 **
MCP-1 (pg/mL)	219.50±12.17	131.95±8.63 *	195.41±27.22 **
Adiponectin
Total (μg/mL)	8.85±0.62	5.33±0.37 *	6.82±1.00
HMW (μg/mL)	4.45±0.46	1.97±0.20 *	3.66±0.62 **
HMW/total adiponectin ratio	0.49±0.03	0.36±0.02 *	0.53±0.04 **
Leptin (ng/mL)	6.91±0.91	8.31±1.09	35.56±10.31 **

BMI: body mass index; MAP: mean arterial pressure; FFA: free fatty acids; MCP: monocyte chemotactic protein; HMW: high-molecular weight.
* 𝑃<0.05 versus nonpregnant control.
** 𝑃<0.05 versus normal pregnancy later than 28 weeks.