Anti-Inflammatory and Antinociceptive Effects of Salbutamol on Acute and Chronic Models of Inflammation in Rats: Involvement of an Antioxidant Mechanism

Table 3

Effects of salbutamol and indomethacin cotton pellet granuloma test.

Drugs	Dose (mg/kg)	Initial weight of the cotton pellets (mg)	Wet weight of cotton pellets that were removed after 8 days (mg)	Inhibition in granuloma formation (%)
Salbutamol	1	7±1	94.0 ± 4.1**	44.3
Salbutamol	2	7±1	116.7 ± 3.0*	30.8
Indomethacin	5	7±1	41.3 ± 3.4**	75.5
Control	—	7±1	168.7 ± 4.3	—

*Significant at 𝑃<0.05 when compared to control, **significant at 𝑃<0.01 when compared to control.