Mediators of Inflammation

Research Article

Altered AKT1 and MAPK1 Gene Expression on Peripheral Blood Mononuclear Cells and Correlation with T-Helper-Transcription Factors in Systemic Lupus Erythematosus Patients

Table 5

Spearman’s rank correlations obtained between cytokines gene expressions in PBMCs and cytokines plasma levels in SLE patients.
Gene SLE (n = 13)
Plasma cytokines
IL-1βIL-2IL-6IL-10IL-12(p70)IFN-γTNF-α
IL-1B       
  r 0.6082      
  P 0.0274      
IL-6       
  r 0.61100.74270.72040.82530.68770.78560.8970
  P 0.02650.00360.00550.00050.00940.0015<0.0001
IL-10       
  r       0.6101
  P       0.0268
Gene Gene
IL-2IL-6IL-10IL-12AIFN-γTGFB2
IL-2      
 r 10.65380.63190.9106 0.7868
 P  0.01530.0205<0.0001 0.0014
IL-6      
 r  10.75820.7180  
 P   0.00270.0057  
IL-10      
 r   10.7813 0.6190
 P    0.0016 0.0241
IL-12A      
 r    10.69050.7796
 P     0.00900.0017
Significant Spearman’s rank correlations coefficients are indicated.
Significance levels set at P values <0.05.