Altered AKT1 and MAPK1 Gene Expression on Peripheral Blood Mononuclear Cells and Correlation with T-Helper-Transcription Factors in Systemic Lupus Erythematosus Patients

Table 6

Spearman’s rank correlations found between MAPK1, AKT1, and Th-transcription factors gene expressions in SLE patients.

SLE (n = 13)
Gene	AKT1	T-bet	STAT4	GATA3	RORC	FOXP3
MAPK1
r	0.9188	0.5659		0.5609	0.6154
P	<0.0001	0.0438		0.0463	0.0252
AKT1
r	1				0.6300
P					0.0210
T-bet
r		1	0.7912	0.9231	0.8958	0.9066
P			0.0013	<0.0001	<0.0001	0.0004
STAT4
r			1	0.7308	0.7253	0.5659
P				0.0045	0.005	0.0438
GATA3
r				1	0.9066	0.9066
P					<0.0001	<0.0001
RORC
r					1	0.7802
P						0.0017

Significant Spearman’s rank correlations coefficients are indicated.
Significance levels set at P values <0.05.