Altered AKT1 and MAPK1 Gene Expression on Peripheral Blood Mononuclear Cells and Correlation with T-Helper-Transcription Factors in Systemic Lupus Erythematosus Patients

Table 7

Spearman’s rank correlations found between gene expressions of AKT1, MAPK1, FOXP3, cytokines, IL-10, and Th-transcription factors.

SLE (n=13)
Gene	AKT1	MAPK1	FOXP3	RORC	GATA3	T-bet
IL-2
r			0.7692
P			0.0021
IL-5
r	0.6970	0.7895	0.6575
P	0.0081	0.0013	0.0106
IL-6
r			0.6484
P			0.0165
IL-10
r		0.5549	0.8022	0.6923	0.7143	0.5604
P		0.0490	0.0010	0.0087	0.0061	0.0463
IL-12A
r		0.5942	0.9051
P		0.0322	<0.0001
IFN-γ
r			0.6703
P			0.0122
TNFSF10
r	0.6556
P	0.0150
TGFB2
r	0.6584	0.6960	0.6990
P	0.0144	0.0082	0.0082

Significant Spearman’s rank correlations coefficients are indicated.
Significance levels set at P values <0.05.