Altered AKT1 and MAPK1 Gene Expression on Peripheral Blood Mononuclear Cells and Correlation with T-Helper-Transcription Factors in Systemic Lupus Erythematosus Patients

Table 8

Spearman’s rank correlation test.

SLE (n = 13)
	CRP^c	N^d		Age	C4^c	L^f	CD38^e	ZAP70^e	CCR6^e
Cytokines^a			Gene^e
IL-1β			IL-2
r	0.5944		r	0.6658
P	0.0415		P	0.0130
IL-2			IL-10
r	0.6671		r	0.6107			0.5915
P	0.0178		P	0.0266			0.0332
IL-6			IL-12A
r	0.6160		r	0.6419
P	0.0329		P	0.0180
IL-10			TGFB2
r	0.6690		r	0.5909
P	0.0174		P	0.0335
IL-13			TNFSF10
r	0.8629		r			−0.5750
P	0.0003		P			0.0398
IFN-γ			TNF-α
r	0.7261		r					0.6740
P	0.0075		P					0.0115
TNF-α			AKT1
r	0.6834		r				0.6061
P	0.0143		P				0.0281
			GATA-3
			r	0.6190
			P	0.0241
			STAT4
			r		0.7836				0.5659
			P		0.0026				0.0438
Calprotectin^b			CCR6
r		0.6593	r		0.7343
P		0.0142	P		0.0065

^aPlasma Cytokines (pg/mL).
^bCalprotectin plasma levels (ng/mL).
^cn = 12.
^dN: Neutrophils.
^eGene: Gene expression, as indicated in legend of Figure 1.
^fL: Lymphocytes.
Significant Spearman’s rank correlations coefficients are indicated.
Significance levels set at P values <0.05.