Clarithromycin Suppresses Human Respiratory Syncytial Virus Infection-Induced Streptococcus pneumoniae Adhesion and Cytokine Production in a Pulmonary Epithelial Cell Line
Figure 2
Effects of CAM and PDTC on RSV-induced RANTES (a), IL-8 (b), and IL-6 (c) production in A549 cells. One hour before RSV infection, CAM or PDTC is added to A549 cell culture at the indicated concentration. A549 cells were infected with the RSV at MOI of 1. After 24 h of infection, the culture supernatants were collected, and each cytokine in the supernatants was determined by ELISA. The experiments were performed in triplicate. The mean value and standard deviation were calculated. Statistical difference was examined by Student’s -test. compared to cytokine production without any reagent treatment in uninfected cells and RSV-infected cells, respectively.
