Circulating Leukotriene B4 Identifies Respiratory Complications after Trauma

Table 1

Summary of patient characteristics and physiologic parameters in the investigated groups (ØPC: no pulmonary complications, PC: pulmonary complications and ctrl, data are presented as mean ± SEM unless otherwise stated).

Patient characteristics	All patients (𝑛=100)	PC (𝑛=30)	ØPC (𝑛=70)	ctrl (𝑛=20)	𝑃 value(PC versus ØPC)
Age (years)	39.2±1.7	42.8±3.4	37.9±1.9	32.3±2.8	0.2241
Sex (male)	76	20	56	7	—
Injury severity score	34.0±1.0	33.7±1.6	34.1±1.3	—	1.0000
Surgery after admission	69.0%	76.7%	70.8%	—	0.6218
Thoracic drainage	34.0%	53.3%	25.7%	—	0.0191
Packed red blood cells (pRBC)/250 mL (24 h)	7.4±1.2	8.6±1.9	7.2±1.5	—	0.2739
Massive transfusion (≥10units pRBC in 24)	20.0%	26.7%	17.4%	—	0.6007
Haemoglobin (g/dL)	11.5±0.3	9.9±0.7	12.6±0.3	—	0.0044
Intubation	73.0%	96.7%	81.4%	—	0.0762
Intubation duration (d)	9.9±1.1	18.4±2.7	6.4±0.8	—	<0.0001
Rotational bed therapy	62.0%	86.7%	51.4%	—	0.0020
Rotational bed Therapy (d)	3.9±0.5	5.3±0.7	3.4±0.6	—	0.0070
Intensive care period (d)	12.8±1.3	22.4±3.1	8.9±0.9	—	<0.0001
Hospital stay	24.1±2.0	32.5±5.2	20.5±1.7	—	<0.0001
Sepsis (𝑛/%)	16/16.0%	11/36.7%	5/7.1%	—	0.0162
Organ failure (𝑛/%)	8/8.0%	5/16.7%	3/4.3%	—	0.3137
MOF (𝑛/%)	4/4.0%	3/10.0%	1/1.4%	—	0.4889
Hospital mortality (𝑛/%)	6/6.0%	3/10.0%	3/4.3%	—	0.6390
LTB4 (pg/mL, interquartile range)	105.9(96.7)	127.8(96.5)	95.6(88)	58.4(72.1)	0.0140