Apoptotic Cells Contribute to Melanoma Progression and This Effect is Partially Mediated by the Platelet-Activating Factor Receptor

<table>PAF does not affect melanoma progression induced by apoptotic cells or carrageenan. Melanoma growth (10<sup>3</sup> viable Tm1 cells) induced by apoptotic cells (10<sup>6</sup>  <i>γ</i>-irradiated Tm1 cells, (a)) or carrageenan (0.1%, (b)) in C57Bl/6 mice did not show any statistical difference between the treatment with PBS or PAF (10 <i>μ</i>g) given by peritumor injection daily for 5 consecutive days.</table>

Mediators of Inflammation

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Figure 2

Figure 2: Apoptotic Cells Contribute to Melanoma Progression and This Effect is Partially Mediated by the Platelet-Activating Factor Receptor 