Research Article
Serum IL-18 Is Closely Associated with Renal Tubulointerstitial Injury and Predicts Renal Prognosis in IgA Nephropathy
Table 2
Clinical and histological data in Rs and NRs patients.
| | Rs patients
(n = 51) | NRs patients
(n = 25) | value |
| | Age (y) | 39.54 ± 11.33 | 37.58 ± 10.32 | 0.61 | | Female, (%) | 23 (45.10%) | 12 (50.00%) | 0.82 | | Smokers, (%) | 9 (17.64%) | 4 (16.00%) | 0.58 | | SBP (mmHg) | 124.4 ± 19.2 | 121.7 ± 15.6 | 0.06 | | DBP (mmHg) | 80.6 ± 12.4 | 77.5 ± 7.5 | 1.35 | | Hemoglobin (g/L) | 125.17 ± 21.17 | 134.58 ± 8.98 | 0.07 | | Albumin (g/L) | 38.03 ± 5.99 | 36.52 ± 5.61 | 0.35 | | Scr (μmol/L) | 101.32 ± 36.56 | 94.73 ± 32.39 | 0.60 | | eGFR (mL/min/1.73 m2) | 73.32 ± 25.27 | 80.85 ± 29.09 | 0.45 | | Urinary protein (g/24 h) | 2.73 (1.65–3.91) | 1.86 (1.28–2.69) | 0.13 | | sIgA (g/L) | 3.05 ± 1.07 | 3.38 ± 0.68 | 0.33 | | sIL-18 (pg/mL) | 348.35 ± 37.05 | 384.06 ± 15.10 | 0.02 | | GGS (%) | 0.22 (0.09–0.43) | 0.25 (0.08–0.50) | 0.67 | | TID | 3.00 (2.00–4.00) | 4.50 (3.00–6.00) | 0.04 |
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