Research Article

Serum IL-18 Is Closely Associated with Renal Tubulointerstitial Injury and Predicts Renal Prognosis in IgA Nephropathy

Table 4

Clinical and histological data between patients with proteinuria above 3.5 g/24 h or not.

Proteinuria lower than 3.5 g/24 h
(n = 57)
Proteinuria above 3.5 g/24 h
(n = 19)
value

Age (y)38.87 ± 10.7637.49 ± 9.980.88
Female, (%)28 (49.12%)11 (57.89%)0.67
Smokers, (%)10 (17.54%)3 (15.79%)0.49
SBP (mmHg)124.54 ± 18.33118.8 ± 14.020.52
DBP (mmHg)79.62 ± 10.9077.24 ± 7.910.56
Hemoglobin (g/L)131.15 ± 19.38119.78 ± 14.040.15
Albumin (g/L)38.21 ± 3.6635.42 ± 8.510.02
Scr (μmol/L)100.32 ± 35.4295.37 ± 35.090.99
eGFR (mL/min/1.73 m2) 80.64 ± 29.000.37
sIgA (g/L)3.13 ± 0.973.26 ± 1.000.62
sIL-18 (pg/mL)346.03 ± 15.52402.94 ± 19.860.02
GGS (%)0.24 (0.14–0.26)0.35 (0.06–0.47)0.05
TID4.00 (3.00–4.00)4.50 (2.00–6.00)0.88