Research Article
Serum IL-18 Is Closely Associated with Renal Tubulointerstitial Injury and Predicts Renal Prognosis in IgA Nephropathy
Table 4
Clinical and histological data between patients with proteinuria above 3.5 g/24 h or not.
| | Proteinuria lower than 3.5 g/24 h (n = 57) | Proteinuria above 3.5 g/24 h (n = 19) | value |
| Age (y) | 38.87 ± 10.76 | 37.49 ± 9.98 | 0.88 | Female, (%) | 28 (49.12%) | 11 (57.89%) | 0.67 | Smokers, (%) | 10 (17.54%) | 3 (15.79%) | 0.49 | SBP (mmHg) | 124.54 ± 18.33 | 118.8 ± 14.02 | 0.52 | DBP (mmHg) | 79.62 ± 10.90 | 77.24 ± 7.91 | 0.56 | Hemoglobin (g/L) | 131.15 ± 19.38 | 119.78 ± 14.04 | 0.15 | Albumin (g/L) | 38.21 ± 3.66 | 35.42 ± 8.51 | 0.02 | Scr (μmol/L) | 100.32 ± 35.42 | 95.37 ± 35.09 | 0.99 | eGFR (mL/min/1.73 m2) | | 80.64 ± 29.00 | 0.37 | sIgA (g/L) | 3.13 ± 0.97 | 3.26 ± 1.00 | 0.62 | sIL-18 (pg/mL) | 346.03 ± 15.52 | 402.94 ± 19.86 | 0.02 | GGS (%) | 0.24 (0.14–0.26) | 0.35 (0.06–0.47) | 0.05 | TID | 4.00 (3.00–4.00) | 4.50 (2.00–6.00) | 0.88 |
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