Research Article
Serum IL-18 Is Closely Associated with Renal Tubulointerstitial Injury and Predicts Renal Prognosis in IgA Nephropathy
Table 6
Cox Regression analysis using to evaluate risk factor for renal function deterioration in patients with IgA nephropathy.
| Parameter | | t | value |
| TID score | 1.96 | 3.69 | 0.001 | sIL-18 (pg/mL) | 1.98 | 2.77 | 0.003 | Baseline Scr (μmol/L) | 0.09 | 0.19 | 0.017 | eGFR (mL/min/1.73 m2) | −0.05 | 0.01 | 0.023 | Proteinuia (g/24 h) | 2.50 | 0.33 | 0.056 | Gender | 0.56 | 0.32 | 0.572 | Age (year) | −0.19 | −3.98 | 0.312 | Smoke history | 0.33 | 0.41 | 0.746 | SBP (mmHg) | −0.03 | −0.27 | 0.760 | DBP (mmHg) | 0.02 | 0.23 | 0.821 | Hemoglobin (g/dL) | 0.22 | 1.43 | 0.739 | sAlb (g/L) | 0.002 | 0.02 | 0.734 | Cholesterol (mmol/L) | 0.07 | 0.59 | 0.653 | Triglyceride (mmol/L) | −0.18 | −1.53 | 0.533 | sIgA (g/L) | 0.18 | 1.97 | 0.812 | Hs-CRP (mg/L) | 0.13 | 1.45 | 0.931 | GSS (%) | −0.04 | −0.36 | 0.602 |
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