A Picrorhiza kurroa Derivative, Picroliv, Attenuates the Development of Dextran-Sulfate-Sodium-Induced Colitis in Mice
Figure 2
Effect of picroliv on histological injury in DSS-induced colitis. Hematoxylin and eosin staining (magnification ×100) of colonic tissue section. (a) Mucosa from control mice did not show any histological modifications; (b) DSS-induced mucosal injury associated with complete destruction of epithelial architecture with loss of crypts and epithelial integrity, submucosal edema, and intense inflammatory cellular infiltration; (c) treatment with picroliv attenuated the disturbances in morphology but caused a mild cellular infiltration.
