Atherogenic Index and High-Density Lipoprotein Cholesterol as Cardiovascular Risk Determinants in Rheumatoid Arthritis: The Impact of Therapy with Biologicals

Table 3

Effects of tocilizumab on atherogenic index and other lipid ratios.

Atherogenic index	Study (ref), patients (𝑁), and lipid ratio’s
Higher	Emery et al. [33] (𝑁=338) LDL/HDL; Genovese et al. [34] (𝑁=803) TC/HDL, LDL/HDL; Smolen et al. [39] (𝑁=418) TC/HDL
Neutral	Kume et al. [21] (𝑁=22) TC/HDL; Kawashiri et al. [36] (𝑁=19) TC/HDL, apoB/apoA-1; Maini et al. [37] (𝑁>50) TC/HDL;
N.A.	Jones et al. [35]; Schultz et al. [38]

N.A.: not assessed.