Calorie Restriction with a High-Fat Diet Effectively Attenuated Inflammatory Response and Oxidative Stress-Related Markers in Obese Tissues of the High Diet Fed Rats
Figure 8
Effect of HFCR on protein expression related to inflammation and oxidative stress in liver. (a) Western blot assay of pIκBα, iNOS, COX-2, Nrf2, and HO-1. (b) densitometric analysis of bands in Western blot. CON: rats fed a control diet (10% kcal fat) ad libitum for the experimental periods, HF: rats fed a high-fat diet (45% kcal fat) ad libitum for the experimental periods, and HFCR: 40% calorie restricted rats fed a high-fat diet for 8–10 weeks after being fed the high-fat diet ad libitum for 11–13 weeks. a.u.: arbitrary unit. Values are means ± SEM, in each. Means for a variable without a common letter differ, .
