Calorie Restriction with a High-Fat Diet Effectively Attenuated Inflammatory Response and Oxidative Stress-Related Markers in Obese Tissues of the High Diet Fed Rats

Table 1

Daily food and energy intakes in the experimental animals.

Group	Before HFCR		After HFCR
	Food intake (g/day)	Energy intake (kcal/day)	Food intake (g/day)	Energy intake (kcal/day)
CON	25.92 ± 0.13^a	99.79 ± 0.50^a	24.72 ± 0.23^a	95.16 ± 0.87^a
HF	23.37 ± 0.13^b	110.53 ± 0.64^b	21.67 ± 0.20^b	102.50 ± 0.94^b
HFCR			13.01 ± 0.04^c	61.56 ± 0.21^c

CON: rats fed a control diet (10% kcal fat) ad libitum for the experimental periods, HF: rats fed a high-fat diet (45% kcal fat) ad libitum for the experimental periods, HFCR: 40% calorie restricted rats fed a high-fat diet for 8–10 weeks after being fed the high-fat diet ad libitum for 11–13 weeks. Values are means ± SEM, 𝑛=20 in each group. Means for a variable without a common letter differ, 𝑃<0.05.