Research Article

Anesthetic Isoflurane Posttreatment Attenuates Experimental Lung Injury by Inhibiting Inflammation and Apoptosis

Figure 3

Treatment with 1.4% ISO reduces NF-κB activation caused by ZY in the lung. (a) Western blot analysis of IκB-α expression in the cytoplasm, (b) protein bands densitometrically quantified and relative amounts of IκB-α protein normalized against β-actin, (c) Western blot analysis of the nuclear levels of NF-κB p65, and (d) protein bands densitometrically quantified and relative amounts of NF-κB p65 protein normalized against histone-3. The respective densitometric analysis of protein bands is from three separate experiments. The animals were treated as described in Figure 1. Data are mean ± SD ( mice per group). * versus sham; # versus ZY + vehicle.
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