Mitochondrial Dysfunction: A Basic Mechanism in Inflammation-Related Non-Communicable Diseases and Therapeutic Opportunities

Figure 6

The complete elimination of mitochondria by autophagy (arrow) is a process linked to mitochondrial fission and fusion. Mitochondria also employ quality-control proteases to eliminate damaged molecules through the transcriptional induction of chaperones or the ubiquitin proteasome quality-control pathway.