Significant Association between Serum Interleukin-6 and Helicobacter pylori Antibody Levels among H. pylori-Positive Japanese Adults

Table 1

Distribution of age, serum anti-H. pylori IgG, interleukin-6 level, and atrophic gastritis by sex.

Characteristics	Men		Women		Total
	𝑛	%	𝑛	%	𝑛	%
Age (years)
20–29	1	1.9	0	0.0	1	0.6
30–39	5	9.3	7	6.7	12	7.6
40–49	3	5.6	18	17.3	21	13.3
50–59	15	27.8	34	32.7	49	31.0
60–69	26	48.1	41	39.4	67	42.4
70–79	4	7.4	4	3.8	8	5.1
Serum anti-H. pylori IgG titer
<50	26	48.1	49	47.1	75	47.5
50–100	19	35.2	35	33.7	54	34.2
101–200	6	11.1	17	16.3	23	14.6
>200	3	5.6	3	2.9	6	3.8
Serum interleukin-6 (pg/mL)
<1.0	3	5.6	13	12.5	16	10.1
1.0-2.0	29	53.7	61	58.7	90	57.0
2.1–3.0	17	31.5	26	33.8	43	27.2
3.1–4.0	5	9.3	4	3.8	9	5.7
Atrophic gastritis
Negative	21	38.9	40	38.5	61	38.6
Positive	11	20.4	20	19.2	31	19.6
Moderate positive	12	22.2	31	29.8	43	27.2
Strong positive	10	18.5	13	12.5	23	14.6
Total	54	100.0	104	100.0	158	100.0