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Mediators of Inflammation
Volume 2013, Article ID 152860, 11 pages
http://dx.doi.org/10.1155/2013/152860
Research Article

Expression of Annexin-A1 and Galectin-1 Anti-Inflammatory Proteins and mRNA in Chronic Gastritis and Gastric Cancer

1Department of Biology, São Paulo State University (UNESP), Campus de São José do Rio Preto, Rua Cristóvão Colombo 2265, 15054-000 São José do Rio Preto, SP, Brazil
2Rio Preto Endoscopy Center, São José do Rio Preto, SP, Brazil
3Endoscopy Service, Hospital de Base, São José do Rio Preto, SP, Brazil
4Legal Medicine Department and Pathology Service, Hospital de Base, São José do Rio Preto, SP, Brazil
5Institute of Anatomical Pathology and Cytopathology, São José do Rio Preto, SP, Brazil

Received 7 May 2012; Accepted 28 December 2012

Academic Editor: Eeva Moilanen

Copyright © 2013 Yvana Cristina Jorge et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. T. Chiba, H. Marusawa, and T. Ushijima, “Inflammation-associated cancer development in digestive organs: mechanisms and roles for genetic and epigenetic modulation,” Gastroenterology, vol. 143, pp. 550–563, 2012. View at Google Scholar
  2. P. Correa, “A human model of gastric carcinogenesis,” Cancer Research, vol. 48, no. 13, pp. 3554–3560, 1988. View at Google Scholar · View at Scopus
  3. T. Robbins and R. S. Cotran, “Stomach,” in Pathologic Bases of Diseases, pp. 787–801, Saunders, Philadelphia, Pa, USA, 6th edition, 2005. View at Google Scholar
  4. L. T. Nguyen, T. Uchida, K. Murakami, T. Fujioka, and M. Moriyama, “Helicobacter pylori virulence and the diversity of gastric cancer in Asia,” Journal of Medical Microbiology, vol. 57, no. 12, pp. 1445–1453, 2008. View at Publisher · View at Google Scholar · View at Scopus
  5. J. Q. Huang, G. F. Zheng, K. Sumanac, E. J. Irvine, and R. H. Hunt, “Meta-analysis of the relationship between cagA seropositivity and gastric cancer,” Gastroenterology, vol. 125, no. 6, pp. 1636–1644, 2003. View at Publisher · View at Google Scholar · View at Scopus
  6. H. Isomoto, Y. Nishi, K. Ohnita et al., “The relationship between plasma and gastric ghrelin levels and strain diversity in Helicobacter pylori virulence,” American Journal of Gastroenterology, vol. 100, no. 6, pp. 1425–1427, 2005. View at Publisher · View at Google Scholar · View at Scopus
  7. C. D. John, F. N. Gavins, N. A. Buss, P. O. Cover, and J. C. Buckingham, “Annexin A1 and the formyl peptide receptor family: neuroendocrine and metabolic aspects,” Current Opinion in Pharmacology, vol. 8, no. 6, pp. 765–776, 2008. View at Publisher · View at Google Scholar · View at Scopus
  8. J. Almkvist and A. Karlsson, “Galectins as inflammatory mediators,” Glycoconjugate Journal, vol. 19, no. 7-9, pp. 575–581, 2002. View at Publisher · View at Google Scholar · View at Scopus
  9. T. S. Gastardelo, A. S. Damazo, J. Dalli, R. J. Flower, M. Perretti, and S. M. Oliani, “Functional and ultrastructural analysis of annexin A1 and its receptor in extravasating neutrophils during acute inflammation,” American Journal of Pathology, vol. 174, no. 1, pp. 177–183, 2009. View at Publisher · View at Google Scholar · View at Scopus
  10. L. Parente and E. Solito, “Annexin 1: more than an anti-phospholipase protein,” Inflammation Research, vol. 53, no. 4, pp. 125–132, 2004. View at Publisher · View at Google Scholar · View at Scopus
  11. V. Gerke, C. E. Creutz, and S. E. Moss, “Annexins: linking Ca2+ signalling to membrane dynamics,” Nature Reviews Molecular Cell Biology, vol. 6, no. 6, pp. 449–461, 2005. View at Publisher · View at Google Scholar · View at Scopus
  12. P. Matarrese, A. Tinari, E. Mormone et al., “Galectin-1 sensitizes resting human T lymphocytes to Fas (CD95)-mediated cell death via mitochondrial hyperpolarization, budding, and fission,” Journal of Biological Chemistry, vol. 280, no. 8, pp. 6969–6985, 2005. View at Publisher · View at Google Scholar · View at Scopus
  13. G. A. Rabinovich, “Galectin-1 as a potential cancer target,” British Journal of Cancer, vol. 92, no. 7, pp. 1188–1192, 2005. View at Publisher · View at Google Scholar · View at Scopus
  14. C. D. Gil, D. Cooper, G. Rosignoli, M. Perretti, and S. M. Oliani, “Inflammation-induced modulation of cellular galectin-1 and -3 expression in a model of rat peritonitis,” Inflammation Research, vol. 55, no. 3, pp. 99–107, 2006. View at Publisher · View at Google Scholar · View at Scopus
  15. J. W. Lim, H. Kim, and K. H. Kim, “Cell adhesion-related gene expression by Helicobacter pylori in gastric epithelial AGS cells,” International Journal of Biochemistry and Cell Biology, vol. 35, no. 8, pp. 1284–1296, 2003. View at Publisher · View at Google Scholar · View at Scopus
  16. Y. R. Chen, H. F. Juan, H. C. Huang et al., “Quantitative proteomic and genomic profiling reveals metastasis-related protein expression patterns in gastric cancer cells,” Journal of Proteome Research, vol. 5, no. 10, pp. 2727–2742, 2006. View at Publisher · View at Google Scholar · View at Scopus
  17. S. Bektas, B. Bahadir, B. H. Ucan, and S. O. Ozdamar, “CD24 and galectin-1 expressions in gastric adenocarcinoma and clinicopathologic significance,” Pathology and Oncology Research, vol. 16, no. 4, pp. 569–577, 2010. View at Publisher · View at Google Scholar · View at Scopus
  18. G. R. Martin, M. Perretti, R. J. Flower, and J. L. Wallace, “Annexin-1 modulates repair of gastric mucosal injury,” American Journal of Physiology, vol. 294, no. 3, pp. G764–G769, 2008. View at Publisher · View at Google Scholar · View at Scopus
  19. G. Yu, J. Wang, Y. Chen et al., “Tissue microarray analysis reveals strong clinical evidence for a close association between loss of annexin A1 expression and nodal metastasis in gastric cancer,” Clinical and Experimental Metastasis, vol. 25, no. 7, pp. 695–702, 2008. View at Publisher · View at Google Scholar · View at Scopus
  20. C. M. Wu, Y. S. Lee, T. H. Wang et al., “Identification of differential gene expression between intestinal and diffuse gastric cancer using cDNA microarray,” Oncology Reports, vol. 15, no. 1, pp. 57–64, 2006. View at Google Scholar · View at Scopus
  21. F. Zhu, C. Xu, Z. Jiang et al., “Nuclear localization of annexin A1 correlates with advanced disease and peritoneal dissemination in patients with gastric carcinoma,” Anatomical Record, vol. 293, no. 8, pp. 1310–1314, 2010. View at Publisher · View at Google Scholar · View at Scopus
  22. P. Lauren, “The two histological main types of gastric carcinoma: diffuse and so-called intestinal-type carcinoma,” Acta Pathologica et Microbiologica Scandinavica, vol. 64, pp. 31–49, 1965. View at Google Scholar · View at Scopus
  23. M. F. Dixon, R. M. Genta, J. H. Yardley et al., “Classification and grading of Gastritis: the updated Sydney system,” American Journal of Surgical Pathology, vol. 20, no. 10, pp. 1161–1181, 1996. View at Publisher · View at Google Scholar · View at Scopus
  24. S. A. Ahrendt, J. T. Chow, S. C. Yang et al., “Alcohol consumption and cigarette smoking increase the frequency of p53 mutations in non-small cell lung cancer,” Cancer Research, vol. 60, no. 12, pp. 3155–3159, 2000. View at Google Scholar · View at Scopus
  25. L. L. Gatti, R. de Lábio, L. C. da Silva, M. D. A. C. Smith, and S. L. M. Payão, “cagA positive Helicobacter pylori in Brazilian children related to chronic gastritis,” Brazilian Journal of Infectious Diseases, vol. 10, no. 4, pp. 254–258, 2006. View at Publisher · View at Google Scholar · View at Scopus
  26. R. M. Peek and M. J. Blaser, “Helicobacter pylori and gastrointestinal tract adenocarcinomas,” Nature Reviews Cancer, vol. 2, no. 1, pp. 28–37, 2002. View at Google Scholar · View at Scopus
  27. A. A. S. Sena, P. J. S. Provazzi, A. M. Fernandes, P. M. Cury, P. Rahal, and S. M. Oliani, “Spatial expression of two anti-inflammatory mediators, annexin 1 and galectin-1, in nasal polyposis,” Clinical and Experimental Allergy, vol. 36, no. 10, pp. 1260–1267, 2006. View at Publisher · View at Google Scholar · View at Scopus
  28. M. C. Duarte, E. Babeto, K. R. M. Leite et al., “Expression of TERT in precancerous gastric lesions compared to gastric cancer,” Brazilian Journal of Medical and Biological Research, vol. 44, no. 2, pp. 100–104, 2011. View at Publisher · View at Google Scholar · View at Scopus
  29. M. W. Pfaffl, “A new mathematical model for relative quantification in real-time RT-PCR,” Nucleic Acids Research, vol. 29, no. 9, article e45, 2001. View at Google Scholar · View at Scopus
  30. M. Moghanibashi, F. R. Jazii, Z. S. Soheili et al., “Proteomics of a new esophageal cancer cell line established from Persian patient,” Gene, vol. 500, pp. 124–133, 2012. View at Google Scholar
  31. J. S. Kang, B. F. Calvo, S. J. Maygarden, L. S. Caskey, J. L. Mohler, and D. K. Ornstein, “Dysregulation of annexin I protein expression in high-grade prostatic intraepithelial neoplasia and prostate cancer,” Clinical Cancer Research, vol. 8, no. 1, pp. 117–123, 2002. View at Google Scholar · View at Scopus
  32. J. P. Rodrigo, J. M. García-Pedrero, J. L. Llorente et al., “Down-regulation of annexin A1 and A2 protein expression in intestinal-type sinonasal adenocarcinomas,” Human Pathology, vol. 42, no. 1, pp. 88–94, 2011. View at Publisher · View at Google Scholar · View at Scopus
  33. R. Silistino-Souza, F. C. Rodrigues-Lisoni, P. M. Cury et al., “Annexin 1: differential expression in tumor and mast cells in human larynx cancer,” International Journal of Cancer, vol. 120, no. 12, pp. 2582–2589, 2007. View at Publisher · View at Google Scholar · View at Scopus
  34. C. K. Yom, W. Han, S.-W Kim et al., “Clinical significance of snnexin A1 expression in breast câncer,” Journal Breast of Cancer, vol. 14, pp. 262–268, 2011. View at Google Scholar
  35. N. Su, X.-Y. Xu, H. Chen et al., “Increased expression of annexin A1 is correlated with K-ras mutation in colorectal cancer,” Tohoku Journal of Experimental Medicine, vol. 222, no. 4, pp. 243–250, 2010. View at Publisher · View at Google Scholar · View at Scopus
  36. W.-Y Kang, W.-T Chen, Y.-C Huang, Y.-C Su, and C.-Y Chai, “Overexpression of annexin 1 in the development and differentiation of urothelial carcinoma,” Kaohsiung Journal of Medical Sciences, vol. 28, pp. 145–150, 2012. View at Google Scholar
  37. Y. F. Liu, P. F. Zhang, M. Y. Li, Q. Q. Li, and Z. C. Chen, “Identification of annexin A1 as a proinvasive and prognostic factor for lung adenocarcinoma,” Clinical and Experimental Metastasis, vol. 28, no. 5, pp. 413–425, 2011. View at Publisher · View at Google Scholar · View at Scopus
  38. C. Y. Lin, Y. M. Jeng, H. Y. Chou et al., “Nuclear localization of annexin A1 is a prognostic factor in oral squamous cell carcinoma,” Journal of Surgical Oncology, vol. 97, no. 6, pp. 544–550, 2008. View at Publisher · View at Google Scholar · View at Scopus
  39. T.-Y. Cheng, M.-S. Wu, J.-T. Lin et al., “Annexin A1 is associated with gastric cancer survival and promotes gastric cancer cell invasiveness through the Formyl Peptide Receptor/Extracellular Signal-Regulated Kinase/Integrin Beta-1-Binding Protein 1 Pathway,” Cancer, vol. 118, no. 23, pp. 5757–5767, 2012. View at Publisher · View at Google Scholar
  40. V. A. Alves, S. Nonogaki, P. M. Wünsch-Filho et al., “Annexin A1 subcellular expression in laryngeal squamous cell carcinoma,” Histopathology, vol. 53, pp. 715–727, 2008. View at Google Scholar
  41. Y. Liu, H. X. Wang, N. Lu et al., “Translocation of annexin I from cellular membrane to the nuclear membrane in human esophageal squamous cell carcinoma,” World Journal of Gastroenterology, vol. 9, no. 4, pp. 645–649, 2003. View at Google Scholar · View at Scopus
  42. K. Monastyrskaya, E. B. Babiychuk, A. Hostettler, U. Rescher, and A. Draeger, “Annexins as intracellular calcium sensors,” Cell Calcium, vol. 41, no. 3, pp. 207–219, 2007. View at Publisher · View at Google Scholar · View at Scopus
  43. T. H. . Sheng, L. X. Rong, Z. Y. Li, J. Bo, and S. Lei, “Tissue and serum galectin-1 expression in patients with colorectal carcinoma,” Hepatogastroenterology, vol. 59, pp. 389–394, 2012. View at Google Scholar
  44. P. Kamper, M. Ludvigsen, K. Bendix et al., “Proteomic analysis identifies galectin-1 as a predictive biomarker for relapsed/refractory disease in classical Hodgkin lymphoma,” Blood, vol. 117, no. 24, pp. 6638–6649, 2011. View at Publisher · View at Google Scholar · View at Scopus
  45. S. Saussez, C. Decaestecker, F. Lorfevre et al., “Increased expression and altered intracellular distribution of adhesion/growth-regulatory lectins galectins-1 and -7 during tumour progression in hypopharyngeal and laryngeal squamous cell carcinomas,” Histopathology, vol. 52, no. 4, pp. 483–493, 2008. View at Publisher · View at Google Scholar · View at Scopus
  46. C. F. Estofolete, S. Zucoloto, S. M. Oliani, A. C. Polli-Lopes, and C. D. Gil, “Myenteric denervation downregulates galectin-1 and -3 expression in gastric carcinogenesis,” Digestive Diseases and Sciences, vol. 56, no. 6, pp. 1637–1644, 2011. View at Publisher · View at Google Scholar · View at Scopus
  47. G. Chen, T. G. Gharib, C. C. Huang et al., “Discordant protein and mRNA expression in lung adenocarcinomas,” Molecular & Cellular Proteomics, vol. 1, no. 4, pp. 304–313, 2002. View at Google Scholar · View at Scopus
  48. D. Greenbaum, C. Colangelo, K. Williams, and M. Gerstein, “Comparing protein abundance and mRNA expression levels on a genomic scale,” Genome Biology, vol. 4, no. 9, article 117, 2003. View at Publisher · View at Google Scholar · View at Scopus
  49. Y. Guo, P. Xiao, S. Lei et al., “How is mRNA expression predictive for protein expression? A correlation study on human circulating monocytes,” Acta Biochimica et Biophysica Sinica, vol. 40, no. 5, pp. 426–436, 2008. View at Publisher · View at Google Scholar · View at Scopus
  50. F. E. Rosa, S. M. Silveira, C. G. T. Silveira et al., “Quantitative real-time RT-PCR and chromogenic in situ hybridization: precise methods to detect HER-2 status in breast carcinoma,” BMC Cancer, vol. 9, article 90, 2009. View at Publisher · View at Google Scholar · View at Scopus
  51. A. Bouman, M. Jan Heineman, and M. M. Faas, “Sex hormones and the immune response in humans,” Human Reproduction Update, vol. 11, no. 4, pp. 411–423, 2005. View at Publisher · View at Google Scholar · View at Scopus
  52. E. Z. F. Ang, H. T. Nguyen, H. L. Sim, T. C. Putti, and L. H. K. Lim, “Annexin-1 regulates growth arrest induced by high levels of estrogen in MCF-7 breast cancer cells,” Molecular Cancer Research, vol. 7, no. 2, pp. 266–274, 2009. View at Publisher · View at Google Scholar · View at Scopus
  53. J. G. Kusters, A. H. M. Van Vliet, and E. J. Kuipers, “Pathogenesis of Helicobacter pylori infection,” Clinical Microbiology Reviews, vol. 19, no. 3, pp. 449–490, 2006. View at Publisher · View at Google Scholar · View at Scopus
  54. R. Tsutsumi, H. Higashi, M. Higuchi, M. Okada, and M. Hatakeyama, “Attenuation of Helicobacter pylori CagA·SHP-2 signaling by interaction between CagA and C-terminal Src kinase,” Journal of Biological Chemistry, vol. 278, no. 6, pp. 3664–3670, 2003. View at Publisher · View at Google Scholar · View at Scopus
  55. C. C. Allison, T. A. Kufer, E. Kremmer, M. Kaparakis, and R. L. Ferrero, “Helicobacter pylori induces MAPK phosphorylation and AP-1 activation via a NOD1-dependent mechanism,” Journal of Immunology, vol. 183, no. 12, pp. 8099–8109, 2009. View at Publisher · View at Google Scholar · View at Scopus
  56. J. J. Yang, L. Y. Cho, S. H. Ma et al., “Oncogenic CagA promotes gastric cancer risk via activating ERK signaling pathways: a nested case-control study,” PLoS ONE, vol. 6, no. 6, Article ID e21155, 2011. View at Publisher · View at Google Scholar · View at Scopus
  57. J. Zhou, Y. Xie, Y. Zhao, S. Wang, and Y. Li, “Human gastrin mRNA expression up-regulated by Helicobacter pylori CagA through MEK/ERK and JAK2-signaling pathways in gastric cancer cells,” Gastric Cancer, vol. 14, pp. 322–331, 2011. View at Publisher · View at Google Scholar · View at Scopus
  58. L. L. Lin, C. N. Chen, W. C. Lin et al., “Annexin A4: a novel molecular marker for gastric cancer with Helicobacter pylori infection using proteomics approach,” Proteomics, vol. 2, no. 4, pp. 619–634, 2008. View at Publisher · View at Google Scholar · View at Scopus
  59. L. L. Lin, H. C. Huang, S. Ogihara et al., “Helicobacter pylori disrupts host cell membranes, initiating a repair response and cell proliferation,” International Journal of Molecular Sciences, vol. 13, pp. 10176–11092, 2012. View at Google Scholar