Expression of Annexin-A1 and Galectin-1 Anti-Inflammatory Proteins and mRNA in Chronic Gastritis and Gastric Cancer

Table 5

Relative expression of ANXA1 and LGALS1 mRNA in chronic gastritis (CG) and gastric adenocarcinoma (GA) groups according to gender, infection by H. pylori, and presence of cagA+ genotype.

Variable	𝐴𝑁𝑋𝐴1		𝐿𝐺𝐴𝐿𝑆1
	CG	GA	CG	GA
Gender
Female	22 (55%)	6 (30%)	22 (55%)	6 (30%)
(mean ± SD)	4.40±1.80	6.67±2.00	0.29±3.55	4.81±3.26
Male	28 (45%)	14 (70%)	28 (45%)	14 (70%)
(mean ± SD)	4.08±2.32	3.25±5.16	0.60±2.61	1.66±2.96
𝑃	0.63	0.04*	0.75	0.10
H. pylori
Positive	16 (40%)	11 (55%)	16 (40%)	11 (55%)
(mean ± SD)	4.04±2.59	3.91±5.48	−0.05±3.97	3.33±3.16
Negative	24 (60%)	9 (45%)	24 (60%)	9 (45%)
(mean ± SD)	4.40±1.60	4.35±4.05	0.75±2.46	1.36±3.23
𝑃	0.47	0.61	0.24	0.73
Genotype cagA
Positive	10 (62.5%)	3 (27.3%)	10 (62.5%)	3 (27.3%)
(mean ± SD)	2.91±2.74	6.40±3.00	−1.57±3.62	2.58±1.26
Negative	6 (37.5%)	8 (72.7%)	6 (37.5)	8 (72.7%)
(mean ± SD)	5.49±1.56	2.77±6.52	1.89±3.74	2.80±3.10
𝑃	0.14	<0.01*	0.09	0.51

∗Significant difference.