TNF-𝜶 Regulates Natriuretic Peptides and Aquaporins in Human Bronchial Epithelial Cells BEAS-2B

Figure 9

Dexamethasone effect on BNP expression. BEAS-2B cells were treated with 1 μM dexamethasone (DEX) and 40 ng/mL TNF-α alone or in combination with DEX, for 24 h. Histograms show BNP gene expression at mRNA (gray bars) and protein (black bars) level. All histograms indicate means±SD of three different cultures each one tested in quadruplicate and expressed as percentage of control (^∗𝑃<0.01, ^∗∗𝑃<0.001, and ^∗∗∗𝑃<0.0001 versus Controls). C: Controls (untreated cells).