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Mediators of Inflammation
Volume 2013, Article ID 164246, 8 pages
http://dx.doi.org/10.1155/2013/164246
Research Article

Characterising Cytokine Gene Expression Signatures in Patients with Severe Sepsis

1Department of Clinical Medicine, Institute of Molecular Medicine, Trinity College Dublin, St James’s Hospital, Dublin 8, Ireland
2Service d’Immunologie, Hôpital Erasme, Brussels, Belgium
3Department of Clinical Immunology, Institute of Molecular Medicine, Trinity College Dublin, St James’s Hospital, Dublin 8, Ireland

Received 13 March 2013; Revised 13 May 2013; Accepted 15 May 2013

Academic Editor: Vera L. Petricevich

Copyright © 2013 Robert Grealy et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Supplementary material gives gene expression data for cytokines measured in patients with severe sepsis at admission to ICU and/or day 7.

Table 4: Cytokine mRNA in medical and surgical patients with sepsis at time of ICU admission. All values are medial and interquartile range. Analysis is by Wilcoxon rank sum test. P values are uncorrected.

Table 5: Cytokine mRNA in patients with severe sepsis with blood samples at time of ICU admission and 7 days later. Analysis is by Wilcoxon rank sign test. P values are uncorrected.

Table 6: Cytokine mRNA of all patients with severe sepsis at time of ICU admission and/or 7 days later. All values are medial and interquartile range. Analysis is by Wilcoxon rank sum test. P values are uncorrected.

  1. Supplementary Material