Characterising Cytokine Gene Expression Signatures in Patients with Severe Sepsis

Table 2

Lymphocyte subsets in patients with severe sepsis and healthy controls. All values are median and interquartile range. Analysis is by Wilcoxon rank sum test.

	Controls	Sepsis	𝑃
𝑁	6	6
T lymphocytes
CD3^+ CCR7^+ CD45RA^−  (%)	6 (1.3–12.9)	4.2 (2.7–10)	ns
CD3^+ CCR7low CD45RA^−  (%)	23.5 (20–31.3)	21 (17–28.8)	ns
CD3^+ CCR7^+ CD45RA^+  (%)	12.7 (4–24.6)	7.6 (5.3–17)	ns
CD3^+ CCR7^− CD45RA^+  (%)	28.2 (6.6–43)	18.1 (14.1–24)	ns
CD3^+ CD127^+  (%)	55 (53–59)	37 (26–43.6)	0.004
CD3^+ CD127^−  (%)	17.5 (14.2–21)	18.7 (7.1–24.7)	ns
CD16^+ CD56^+  (%)	8.3 (4.9–12.3)	1.9 (1–14)	ns
Monocytes
CD14^+	3.1 (2.8–3.2)	1.5 (1.3–2.9)	ns
CD16^+	1.6 (0.8–3.2)	0.6 (0.4–1.2)	0.06
CD14^+/16^+	0.1 (0.1–0.2)	0.2 (0.1–1)	ns