Induction of Tumor Necrosis Factor (TNF) Release from Subtypes of T Cells by Agonists of Proteinase Activated Receptors
Induction of upregulated expression of TNF in subtypes of purified T cells. Isolated T cells were incubated with trypsin or thrombin for 16 h at 37°C before being analyzed by flow cytometer. (a) Numbers within the large gated regions indicate the percentage of TNF expression cells among different subtypes of T cells. (b) The mean ± SEM data represented the percentage of TNF + cells in different subtypes of T cells indicated for four separate experiments. * in comparison with medium alone control. † compared with the response to the corresponding uninhibited control.