Circulating C19MC MicroRNAs in Preeclampsia, Gestational Hypertension, and Fetal Growth Restriction

Table 1

Correlation between Doppler ultrasonography parameters and C19MC microRNAs expression levels and plasmatic concentrations.

	Spearman’s rank correlation
	Absolute quantification						Relative quantification
	A. umbilicalis PI		Middle cerebral artery PI		Cerebroplacental ratio		A. umbilicalis PI		Middle cerebral artery PI		Cerebroplacental ratio
	𝜌	𝑃	𝜌	𝑃	𝜌	𝑃	𝜌	𝑃	𝜌	𝑃	𝜌	𝑃
miR-516-5p	−0.023	0.845	−0.393	0.005	−0.219	0.125	−0.040	0.736	−0.307	0.030	−0.190	0.183
miR-517*	0.032	0.791	−0.328	0.020	−0.215	0.131	0.073	0.542	−0.288	0.041	−0.269	0.060
miR-518b	−0.025	0.834	−0.152	0.269	−0.074	0.606	−0.019	0.872	−0.220	0.120	−0.167	0.242
miR-520a*	0.092	0.441	−0.314	0.027	−0.261	0.050	0.085	0.477	−0.339	0.017	−0.339	0.018
miR-520h	0.016	0.893	−0.238	0.093	−0.178	0.214	0.038	0.748	−0.256	0.071	−0.219	0.126
miR-525	0.009	0.941	−0.358	0.011	−0.190	0.183	−0.028	0.812	−0.357	0.012	−0.185	0.194
miR-526a	0.156	0.196	−0.304	0.032	−0.340	0.017	0.131	0.277	−0.286	0.043	−0.329	0.021

The association between the plasmatic concentration (absolute quantification) and gene expression levels (relative quantification) of C19MC microRNAs and Doppler ultrasonography parameters such as arteria umbilicalis pulsatility index, middle cerebral artery pulsatility index, and cerebroplacental ratio.
PI: pulsatility index; 𝜌: Spearman’s correlation coefficient; P: level of significance; bold font: statistically significant results.