Research Article

Toll-Like Receptor 9 Promotes Cardiac Inflammation and Heart Failure during Polymicrobial Sepsis

Figure 6

Left ventricular recordings of hemodynamic parameters and RT-qPCR of iNOS expression 18 hours after CASP surgery in the heart. (a)–(g) The measured parameters were (a) heart rate (HR), (b) left ventricular systolic pressure (LVSP), (c) stroke volume (SV), (d) cardiac output (CO), (e) maximal first derivative of pressure rise ( ), (f) maximal first derivative of pressure fall ( ), and (g) stroke work (SW). (h) Time course of iNOS mRNA expression in the heart in WT and TLR9-D mice 6 and 18 h after CASP. (*:    ; mean  ±  SEM).
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