Oncostatin M and TLR-4 Ligand Synergize to Induce MCP-1, IL-6, and VEGF in Human Aortic Adventitial Fibroblasts and Smooth Muscle Cells

<table>MCP-1 and IL-6 responses to gp130 cytokines by HAoAF. HAoAFs were stimulated with increasing doses of LPS alone or with 5 ng/mL LIF ((a), (e)), IL-31 ((b), (f)), IL-11 ((c), (g)), or IL-6 (d) as indicated. Supernatants were collected and analyzed by ELISA for MCP-1 ((a)–(d)) or IL-6 ((e)–(g)). Results are representative of multiple separate experiments.</table>

Mediators of Inflammation

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Figure 2

Figure 2: Oncostatin M and TLR-4 Ligand Synergize to Induce MCP-1, IL-6, and VEGF in Human Aortic Adventitial Fibroblasts and Smooth Muscle Cells 