Oncostatin M and TLR-4 Ligand Synergize to Induce MCP-1, IL-6, and VEGF in Human Aortic Adventitial Fibroblasts and Smooth Muscle Cells
MCP-1 and IL-6 responses to gp130 cytokines by HAoAF. HAoAFs were stimulated with increasing doses of LPS alone or with 5 ng/mL LIF ((a), (e)), IL-31 ((b), (f)), IL-11 ((c), (g)), or IL-6 (d) as indicated. Supernatants were collected and analyzed by ELISA for MCP-1 ((a)–(d)) or IL-6 ((e)–(g)). Results are representative of multiple separate experiments.