Oncostatin M and TLR-4 Ligand Synergize to Induce MCP-1, IL-6, and VEGF in Human Aortic Adventitial Fibroblasts and Smooth Muscle Cells

<table>Regulation of steady state mRNA levels of CD14 and OSMR<i>β</i>. HAoAFs ((a)–(d)) and HAoSMCs ((e)–(h)) were stimulated with LPS (10 ng/mL) or OSM (0.5, 5 ng/mL), and steady state mRNA levels of TLR-4, CD14, OSMR<i>β</i>, and gp130 were measured by qRT-PCR 6 hours after stimulation.</table>

Mediators of Inflammation

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Figure 8

Figure 8: Oncostatin M and TLR-4 Ligand Synergize to Induce MCP-1, IL-6, and VEGF in Human Aortic Adventitial Fibroblasts and Smooth Muscle Cells 