4-Methoxycarbonyl Curcumin: A Unique Inhibitor of Both Inflammatory Mediators and Periodontal Inflammation
Figure 6
Inhibition of NFκB phosphorylation by CMC 2.5 in PBMC cells. PBMC cells (5 × 104 cells/well) were cultured in serum-free media (37°C, 95% air, 5% CO2) for 18 hours with LPS (P. gingivalis, 50 ng/mL) or vehicle alone. CMC 2.5 was added at a final concentration of 5 μM. Following the incubation, cells were fixed and phosphorylation of NFκB was analyzed by CASE cellular activation of signaling ELISA kit. *.
