4-Methoxycarbonyl Curcumin: A Unique Inhibitor of Both Inflammatory Mediators and Periodontal Inflammation

Table 1

Potency of CMC 2.5 as an MMP inhibitor.

Test compounds	MMP-9		MMP-13
	IC50 (μM)	Maximum inhibition (%)	IC50 (μM)	Maximum inhibition (%)
1,10-Phenanthroline	9	100	4	100
Curcumin	29	58	110	53
CMC 2.5	16	72	15	69