Clinical Study
Plasma Granzyme B in ST Elevation Myocardial Infarction versus Non-ST Elevation Acute Coronary Syndrome: Comparisons with IL-18 and Fractalkine
Table 2
Demographic data and biochemical parameters in STEMI and NSTEMI/UA groups.
| Groups | NSTEMI/UA | STEMI | | Factor/ | 14 | 22 |
| Age (years) | 50.5 ± 0.75 | 50.32 ± 0.63 | NS | Sex (M/F) | 8/6 | 18/4 | NS | BMI (kg/m2) | 29 ± 0.68 | 27.95 ± 0.31 | NS | Current smoker, (%) | 5 (36% ) | 9 (41%) | NS | Prior ACS, (%) | 11 (78%) | 5 (23%) | | SBP (mmHg) | 130.71 ± 6.06 | 125 ± 5.29 | NS | DBP (mmHg) | 80.7 ± 5.6 | 76.8 ± 2.7 | NS | Hypertension, (%) | 8 (57%) | 12 (55%) | NS | HR (bpm) | 83.3 ± 2.1 | 85.3 ± 3.2 | NS | LVEF (%) | 51.3 ± 3.1 | 47.6 ± 2.2 | NS | Peak CK (IU/L) | 407.8 ± 121.2 | 1874.4 ± 231 | <0.001 | Peak CK-MB (IU/L) | 88.3 ± 22.6 | 235.6 ± 24.3 | <0.001 | Treatment (BB/CCB/ACEI/diuretics/nitrates/statins) | 13/0/8/1/4/13 | 11/2/13/4/2/19 | | TAG (mmol/L) | 1.23 ± 0.04 | 1.27 ± 0.02 | NS | TC (mmol/L) | 5.04 ± 0.13 | 5.34 ± 0.09 | NS | HDL-C (mmol/L) | 0.9 ± 0.04 | 0.92 ± 0.03 | NS | LDL-C (mmol/L) | 3.52 ± 0.12 | 3.73 ± 0.05 | NS | LDL-C/HDL-C | 4 ± 0.2 | 4.15 ± 0.2 | NS | TC/HDL-C | 5.7 ± 0.3 | 5.9 ± 0.2 | NS | Hypercholesterolemia, (%) | 5 (36%) | 15 (68%) | NS | hsCRP (mg/L) | 6.4 ± 0.5 | 11.3 ± 0.6 | <0.001 | GZB (pg/L) | 158.1 ± 9.7 | 254.6 ± 21.8 | <0.01 | IL-18 (pg/mL) | 99.8 ± 3.6 | 92 ± 3.6 | NS | FKN (pg/mL) | 598.2 ± 32 | 662.1 ± 30.3 | NS |
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Results are mean ± SEM. ACEI: angiotensin converting enzyme inhibitor; BB: beta blocker; CCB: calcium channel blocker; CK: creatine kinase; CK-MB: creatine kinase MB fraction; DBP: diastolic blood pressure; HDL-C: high density lipoprotein cholesterol; HR: heart rate; LDL-C: low density lipoprotein cholesterol; LVEF: left ventricular ejection fraction; NS: not significant; SBP: systolic blood pressure; TAG: triacylglycerol; TC: total cholesterol.
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