Plasma Granzyme B in ST Elevation Myocardial Infarction versus Non-ST Elevation Acute Coronary Syndrome: Comparisons with IL-18 and Fractalkine

Table 3

Changes in blood levels of measured markers in STEMI and NSTEMI/UA groups.

Groups	Controls	NSTEMI/UA		STEMI
Factor/𝑛	12	14		22
		First day	Third day	First day	Third day
hsCRP (mg/L)	0.7 ± 0.1	6.4 ± 0.5*	4.7 ± 0.5^*‡‡	11.3 ± 0.6*	7.3 ± 0.6∗¶
GZB (pg/L)	122.3 ± 4.2	158.1 ± 9.7^†	187.3 ± 10.7^*‡	254.6 ± 21.8*	320.5 ± 22.7∗¶
IL-18 (pg/mL)	53.7 ± 2.8	99.8 ± 3.6*	97.9 ± 4.7*	91.2 ± 5.6*	93.5 ± 5.2*
FKN (pg/mL)	388.8 ± 28.8	598.2 ± 32*	548.9 ± 26∗§	662.1 ± 30.3*	587 ± 25.1∗¶

Results are mean ± SEM.
^∗𝑃<0.001 ACS subgroup compared to control group.
^†𝑃<0.01 ACS subgroup compared to control group.
^‡‡𝑃<0.001 third day NSTEMI/UA compared to first day NSTEMI/UA.
^‡𝑃<0.01 third day NSTEMI/UA compared to first day NSTEMI/UA.
^§𝑃<0.05 third day NSTEMI/UA compared to first day NSTEMI/UA.
^¶𝑃<0.001 third day STEMI compared to first day STEMI.