Evaluation of Clinical and Immunological Responses: A 2-Year Follow-Up Study in Children with Allergic Rhinitis due to House Dust Mite

Table 2

Mean (SD), median (IQR), and number of different variables for year 0 and year 2.

	Year 0					Year 2
	Mean	SD	Median	IQR	𝑁	Mean	SD	Median	IQR	𝑁
Clinical symptoms
Nose (score from 0–12)	3.8	2.2	3.62	3.46	59	2.3	1.95	1.84	2.06	52
Eye (score from 0–9)	1.15	1.32	0.67	1.39	59	0.65	1.1	0.21	0.79	52
Lung (score from 0–6)	0.87	1.13	0.37	1.33	59	0.36	0.9	0.028	0.15	52
HDM-specific skin test
Early skin test (HEIC)	1.72	0.61	1.69	0.76	52	1.96	0.78	1.7	0.87	42
Late skin test (mm^2)	871.4	771.6	759.2	1389.8	59	1112.4	904.6	1044.5	1418.28	42
HDM-specific proinflammatory response
Specific IgE (kU/L)	43.23	34.78	38.1	62.45	59	47.58	34.81	45.6	62.3	53
Proliferation (SI)	6.84	6.18	4.78	5.52	59	5.59	6.73	3.29	5.22	41
IL-5 (pg/mL)	892.93	1963.66	329.66	793.15	59	384.4	549.35	194.82	515.00	41
IL-13 (pg/mL)	848.54	1243.31	313.05	1206.3	59	875.31	783.25	1183.44	1494.64	41
IFN-gamma (pg/mL)	97.81	123.61	55.67	139.94	59	58.39	101.85	26.93	72.73	41
HDM-specific regulatory response
CD4^+CD25^hi (% of CD3^+)	0.44	0.26	0.39	0.32	59	0.88	0.46	0.73	0.44	41
FoxP3 (relative expression)	3.22	2.41	2.39	2.47	59	2.8	1.75	2.4	2.65	41
IL-10 (pg/mL)	81.75	157.33	21.32	95.02	59	21.81	39.0	9.24	24.7	41
TGF-beta (pg/mL)	105.13	258.26	0.00	27.27	59	221.35	383.86	58.72	305.75	41

SD: standard deviation.
IQR: Inter Quartile Range.